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Cryofaxol (Cyclophosphamide)

Cryofaxol is used alone or in combination with other medications to treat Hodgkin's lymphoma (Hodgkin's disease) and non-Hodgkin's lymphoma (types of cancer that begin in a type of white blood cells that normally fights infection); cutaneous T-cell lymphoma (CTCL, a group of cancers of the immune system that first appear as skin rashes); multiple myeloma (a type of cancer of the bone marrow); and certain types of leukemia (cancer of the white blood cells), including chronic lymphocytic leukemia (CLL), chronic myelogenous leukemia (CML), acute myeloid leukemia (AML, ANLL), and acute lymphoblastic leukemia (ALL). It is also used to treat retinoblastoma (cancer in the eye), neuroblastoma (a cancer that begins in nerve cells and occurs mainly in children), ovarian cancer (cancer that begins in the female reproductive organs where eggs are formed), and breast cancer. Cryofaxol is also used to treat nephrotic syndrome (a disease that is caused by damage to the kidneys) in children whose disease has not improved, has gotten worse, or has come back after taking other medications or in children who experienced intolerable side effects with other medications. Cryofaxol is in a class of medications called alkylating agents. When Cryofaxol is used to treat cancer, it works by slowing or stopping the growth of cancer cells in your body. When Cryofaxol is used to treat nephrotic syndrome, it works by suppressing your body's immune system.

Other names for this medication:
Cyclophosphamide, Cytoxan, Ciclofosfamida, Cryofaxol, Cycloblastin, Cycloxan, Cycram, Endoxan, Endoxana, Genoxal, Neosar, Procytox, Sendoxan,

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Cryofaxol is also sometimes used to treat a certain type of lung cancer (small cell lung cancer; SCLC). It is also used to treat rhabdomyosarcoma (a type of cancer of the muscles) and Ewing's sarcoma (a type of bone cancer) in children. Talk to your doctor about the risks of using this medication for your condition.

This medication may be prescribed for other uses; ask your doctor or pharmacist for more information.

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Shortly after single intraduodenal injections of salicylamide, salicylamide in free and conjugated forms (sulfate and glucuronide) appeared in the circulating blood. To optimize bone health, accumulating scientific findings support intakes of calcium and vitamin D exceeding current Recommended Dietary Allowances (RDAs) for these nutrients. Levels and confounders of morning cortisol collected from adolescents in a naturalistic (school) setting. Sedation is an important step in the management of patients with hypercyanotic spells associated with tetralogy of Fallot (TOF) to ameliorate and prevent recurrence of cyanosis. The Arp2/3 complex is then able to bind to N-WASP and to proceed with its job of initiating the assembly of actin monomers into actin filaments.

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The equilibrium state is attained in 30 min in all the considered systems. Early fathering as a predictor of later psychosocial functioning among preschool children with behavior problems. Effect of the agents of general anesthesia on mice after microwave irradiation

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However, the plasma concentration of ICG was significantly higher in BC rats at corresponding time intervals than in control rats throughout the experimental period. Temporal variations in menarcheal age in the Bologna province (northern Italy) were investigated in a sample of 2930 women born between 1930 and 1973, examined by retrospective method. From our data, obtained by Radioimmunoassay, anti-HBc titers I:I000 seem to indicate an ongoing or recent viral replication, being probative, even in the absence of the HBsAg marker, for the viral etiology. Bullock and simpler systems in comparative and integrative neurobiology.

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Effect of sodium cyanate on the seizures susceptibility of mice. Intravenous injection of telithromycin significantly lowered blood pressure in anaesthetized rats. Cytophotometry of feulgen-naphtol yellow S stained liver cells--a computerized method for the calculation of nuclear protein. Anesthetizing solar-powered sea slugs for photobiological studies.

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The rates of synthesis and degradation of pyruvate dehydrogenase were not affected significantly by diabetes. Is TCR beta expression an essential event in early thymocyte development? Analysis of preoperative and postoperative lung scintigraphy in patients undergoing elective hip surgery. Cerebral blood flow, glucose metabolism and tunel-positive cells in the development of ischemia. Their clinical signs were saccadic eye movement, dysarthria, rigidity, bradykinesia and postural instability.

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No significant morphologic abnormality in cell-wall structures of antibiotic-exposed cells could be detected by either electron microscopy or the fluorescent antibody staining. Quantitative analysis revealed no association between cell morphology and firing properties.

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Under baseline conditions, responses to the endothelium-dependent agonist acetylcholine were not affected in either aorta or the basilar artery in vitro. Newer approaches to treatment of liver disease in the alcoholic. Two cases of fibromatosis of the breast, characterized by a proliferation of spindle cells containing intracytoplasmic, spherical, eosinophilic inclusion bodies, are reported. We have used primers of this type to produce genetic markers that can distinguish even between laboratory versus wild populations as well as subpopulations of flies from more broadly defined geographic localities, such as within the Hawaiian islands. Laparoscopic pelvic lymph node dissection for staging of prostatic cancer.

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Platelet deposition and release of growth factors have been postulated to be important in initiating the cellular growth response after vascular injury. Temporal Discrimination and Temporal Bisection tasks, in the range of 100 to 1,000 milliseconds, and Time estimation and Time production tasks, in the range of 5 to 60 seconds, were used to assess sub- and multi-second time perceptions, respectively.

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Further southern hybridization indicated that the type I DHFR gene was located on plasmids. The lymph fluid is of recipient origin and its collection appears to be related to use of a high-dose immunosuppressive regimen and to a conscious decision to avoid the use of postoperative surgical drains.

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The effects of local irradiation and intraperitoneal injection of cisplatinum (CDDP) and VP-16 were examined in the sequential 31P magnetic resonance spectroscopy (MRS) in testicular cancer (TC-1) and bladder tumor (BT-8) of human origin, serially transplanted in nude mice. The effects of self-exposure instructions on agoraphobic outpatients. Accumulating biochemical and genetic data therefore suggest that SH2-containing PTPs might have a physiological role in intracellular signal transduction. This review describes the structure, distribution, function, and ligand recognition characteristics of P2X receptors, which comprise seven distinct subunits that can function as both homo- and hetero- polymers.

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tuberculosis isolates in Switzerland were obtained from 14 laboratories. This is particularly true in diseases of the optic nerve and chiasm, and in systemic diseases of the nervous system in which the visual apparatus is also affected. In the present study, we analyzed the consequences of the binding of p53 to CK2 for the enzymatic activity of CK2 in vitro and in vivo. Q/D was two to four times more active than vancomycin and MIC values varied from 0.5-2 according to the species. Street drug use, and alcohol abuse among young adults from a high social class range were studied in the posh seaside resort of Punta del Este (Uruguay) during the (austral) summer vacation (February 1993).

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It is concluded that the mechanism of passive ion transport across the tBLM seems to follow the transient pore model rather than the solubility-diffusion model. Association of paraoxonase gene cluster polymorphisms with ALS in France, Quebec, and Sweden. Furthermore, obtaining reliable peptide maps and meaningful sequence data using MS analysis requires not only the separation of the digested peptides but also strictly defined proteolysis conditions. Several nuclear import pathways, by contrast, were not affected by the Nup214 fragments. Correlation analyses revealed significant positive correlations between the percentage of cells immunopositive for 8-OHdG or 4-hydroxy-2-nonenal and markers of mitochondrial apoptosis.

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A method for estimation of clemastine in human plasma has been developed. Further studies are needed to determine the optimal combinations of these agents in metastatic disease and to assess their impact in the adjuvant setting. We demonstrate spatial control of optical near-fields by femtosecond phase shaping in one-dimensional plasmonic structures.

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There is no change in the tubular glucose absorption of glucose loaded rats. Aerobiology of common environmental allergens: sizes of allergen carrying particles. By analysis of CIDEC expression in 65 human tissues, we conclude that human CIDEC is predominantly expressed in subcutaneous adipocytes.

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The effect of the GABA receptor agonist gamma-hydroxybutyric acid (GHBA) on brain catecholamine concentration was investigated in 1 to 28 day old rats. T cells from CSA1M-bearing mice have high levels of IL-12 responsiveness, whereas cells from Meth A-bearing mice display marginal levels of responsiveness. The ductular lumen was surrounded by two ductular cells and ampullary dilated at the canalicular side. To assess the changes in viscosity of peritoneal fluid during laparoscopic exposure to CO2 insufflation.

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The increased duodenal acid load gives rise to islands of gastric mucosa in the proximal duodenum. Elevated plasma homocysteine levels in centenarians are not associated with cognitive impairment. Effect of treatment with growth hormone on somatostatin in the median eminence of hypophysectomized rats. Himachalol has been identified as the major antispasmodic constituent in the wood of Cedrus deodara. Both components were thermoprecipitable and carried identical antigenic determinants.

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Effect of laser arytenoidectomy on respiratory stridor caused by multiple system atrophy. Here, we tested the hypothesis that skin grafts prevent rejection after simultaneous peptide administration and skin grafting. Propolis is a natural product of bees which exhibits an antimicrobial effect.

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Overexpression screens and sensitized phenotypes, therefore, may help identify the many factors that are expected to be involved in cytokinesis but have not been discovered by previous genetic screens. These findings provide new insight in the mechanisms governing monocyte survival in the inflamed tissue, representing a crucial aspect of host defence and maintenance of homeostasis.

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Salivary cortisol levels were measured before and after scanning. Chlordane-dosed offspring exhibited sex- and dose-dependent effects on testosterone levels, behavioral tests, and body weight conducted between postnatal Days 77 and 85. In this case, a good prognosis was obtained by frequent local resection and adjuvant chemotherapy for metachronous multiple metastases. We identified growth conditions under which Francisella novicida produces abundant OMV. In order to perform this task, adapter proteins are equipped with particular protein-protein and/or protein-lipid interaction modules allowing them to communicate with other signalling proteins.

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The risk factors for retinal detachment were young patients, long eye axis and posterior capsulotomy. Tubular lipidosis is a commonly observed histological lesion in proteinuric renal diseases. The aim was to determine the prevalence of persistent respiratory symptoms and bronchial hyper-responsiveness due to reactive airways dysfunction syndrome in a population of construction workers at moderate to high risk of developing the syndrome, at an interval of 18 to 24 months after multiple exposures to chlorine gas during renovations to a pulp and paper mill. Potassium-stimulated ATPase activity and hydrogen transport in gastric microsomal vesicles.

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Currently, the available libraries mainly target the known protein genes in human and mouse. A Blue Cross and Blue Shield medical director explains some practical applications, including outcomes evaluation, provider selection and practice pattern comparisons. The medial approach to the sural vessels to facilitate microanastomosis about the knee.

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The relationship between chemiluminescence and lipid peroxidation in rat hepatic microsomes. Seventeen patients responded to melatonin (12 DSPS, five non-24). However, their possible roles (beyond intercellular signalling) as well as their specific phenotype in the kidney remain to be established. This paper records our experience with 14 cases of extra temporal reconstruction of the facial nerve, utilizing the cutaneous branch of the radial nerve as an autograft. Tfm mutant mice respond to nonandrogenic stimuli of erythropoiesis.

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Analysis of the prevalence of retinopathies in a diabetic population Preparation and biological activity of four epiprogoitrin myrosinase-derived products. We found no significant differences between the human femoral heads and the fat-filled thirty-pore-per-inch foam models in all measured variables (pressures at the top, chamfer and outer wall, temperature at the 5-mm and 15-mm subsurface).

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Clinical data suggest that switching from thymidine analogues to a tenofovir-containing regimen can benefit patients with lipid abnormalities or lipoatrophy. Most exacerbations were caused by Haemophilus influenzae or Streptococcus pneumoniae.

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The phytoplasma life cycle involves replication in insects and plants. Phenylthiocarbamide (PTC) taste sensitivity in selected populations of the Isle of Man and Cumbria. Medullary sponge kidney: abnormalities of renal tubular and glomerular function, and their relationship to clinical features. A microsurgical epididymal sperm aspiration procedure was performed in the husbands, followed by intracytoplasmic sperm injection of oocytes recovered from the wives. Different degrees of morbidity, in the white mouse, induced by Nocardia brasiliensis, Nocardia asteroides and Nocardia caviae.

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Nowadays, these techniques enable early diagnosis of this disease and based on that an adequate treatment. The balance between protective immunity and pathogenesis in tropical theileriosis: what we need to know to design effective vaccines for the future. The defect vWF gene carried by heterozygote family members could be compensated by a normal allele. Homophobia, lack of knowledge, lack of emotional involvement, and fear of the unknown predicted 57 percent of the variance in fear of contagion. No treatment was implemented before peritoneal fluid and blood sample collection.

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The enhancement is due to removal of rapidly dividing cells from the spleen. The need for histological confirmation of suspected inoperable malignant tumours is stressed. The experiments were carried out on male Wistar rats (200-250 g) divided into four groups: sedentary, exercised for 30 min, 90 min, and until exhaustion. Earlobe keloids usually appear as shiny, smooth, globular growths on one or both sides of the earlobe.

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To review the outcome of resection of the suprarenal or infrarenal inferior vena cava (IVC) and possible indications for prosthetic replacement. Adipocyte formation in human adult adipose tissue (hAT) originates from resident progenitor cell differentiation in the stroma vascular fraction of the AT. We illustrate the method on data from a lymphoma study, and on a dataset containing samples from eight different cancers. We report a case of a carcinoma in situ arising in a tubulovillous adenoma of the distal common bile duct causing obstructive jaundice.

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Glypican-3 modulates BMP- and FGF-mediated effects during renal branching morphogenesis. cuprina are defective in the production of the brown screening pigment xanthommatin. This article reviews issues related to the implementation, efficacy, and accuracy of SMBG and discusses factors that can confound results of SMBG during pregnancy. Moreover, pretreatment with MF inhibits sepsis-activated mitogen-activated protein kinases and nuclear factor kappa-light-chain-enhancer of activated B proteus uti bactrim treatment cells signaling, resulting in inhibiting production of proinflammatory mediators.

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