on all orders above $300.00

FREE Pills!


for free with every order



Less than in your
local pharmacy

Search by letter:


Enter coupon: (if you have one)

Klopidogrel (Clopidogrel)

Klopidogrel is one of the most commonly prescribed medications because of its ability to improve clinical outcomes for a broad range of cardiovascular conditions. After patent protection expired for Klopidogrel in 2012, many healthcare systems adopted generic Klopidogrel as a strategy to reduce healthcare costs.

Other names for this medication:
Clopidogrel, Plavix, Anclog, Anlet, Antiplar, Artevil, Clavix, Clopicard, Clopilet, Clopivas, Deplatt, Diloxol, Duoplavin, Expansia, Farcet, Globel, Grepid, Iscover, Karum, Klopidogrel, Nabratin, Narutis, Nefazan, Noklot, Pidocar, Pidogrel, Pladex, Plagerine, Planor, Tisten, Troken, Trombex, Vaclo, Zyllt,

Similar Products:
Fugacar, Lorzaar, Cefuroxime, Xiclav, Klomeprax, Novofen, Furozenol, Inhibitron, Enapren, Amrizole, Cepodem, Aldezol, Requip, Secam, Remeron, Ipproton, Velamox, Silagra, Macropen, Imox, Donepezil, Zopral, Ocam, Indolan, Primazol, Omeprazol, Trihexy, Nestrolan, Zanaflex, Lipanthyl, Agrocin, Zotral, Ginarsan, Ocuvir, Beclabuvir, Vodelax, Lansoprol, Omezole, Sertima, Locimez, Ataraxone, Activir, Gabapentin,

Klopidogrel is also sometimes used to prevent blood clots in people with atrial fibrillation (a condition in which the heart beats irregularly). Talk to your doctor about the possible risks of using this medication for your condition.

This medication may be prescribed for other uses; ask your doctor or pharmacist for more information.

klopidogrel lek side effects

By contrast, the promoter activity of HBV strains isolated from HCC patients is increased when 1762T and 1764A are reversely mutated into 1762A and 1764G, respectively. Livers of turkeys fed low and high glucosinolate rapeseed meal diets for 16 weeks were examined ultrastructurally. Changes in depression and quality of life in obese individuals with binge eating disorder: bariatric surgery versus lifestyle modification.

klopidogrel lek side effects

The cultivation of bone marrow in agar was shown to form colonies consisting of haemopoietic cells as well as of stromal elements. In vivo and in vitro effects of ghrelin/motilin-related peptide on growth hormone secretion in the rat. Gentamicin alone may be nephrotoxic and should be given with particular caution to the elderly and those with even mild kidney abnormalities.

klopidogrel lek side effects

Pneumococcal disease and its prevention with polyvalent pneumococcal polysaccharide vaccines--a review. The close temporal and geographic associations between the clinical presentation and the development of AKI strongly suggest an association between these SPICE preparations and AKI. In all cases the implant was removed and further haemorrhage has not occurred. The guanidino compounds are detected with a fluorometer, which monitors the fluorescent guanidine derivatives produced by the reaction of the eluted constituents with 9,10-phenanthrenequinone.

klopidogrel lek side effects

Epizootiology and management of feline leukemia virus in the Florida puma. In a two-period rearing trial (1st to 24th and 24th to 45th experimental day) using 72 early-weaned piglets, the optimal vitamin-B6 requirement was determined on the basis of different performance criteria and biochemical parameters. The co-administration of oral naloxone PR with oxycodone PR improves patient assessment of analgesic opioid therapy for severe chronic pain, in terms of both efficacy and tolerability. Selective blood aldosterone levels were just within significant values.

klopidogrel lek side effects

ANCA has also contributed to the diagnosis and classification of rapidly progressive glomerulonephritis, in which there is now firmer evidence to support the use of plasma exchange. The study aimed to define early clinical outcomes, and medium term morphological changes, following endovascular treatment of acute (AAD) and chronic (CAD) Type B aortic dissections.

klopidogrel lek side effects

The blockade of beta-adrenergic receptors alone has proved to be less effective than the combined administration of oxprenolol and clortalidone or of oxprenolol and phentolamine. However, the benefit relies on the level of competence of the users and tailored training is needed to answer specific questions. Embryos first transferred on Day 3 were slightly accelerated in their development, but retained the ability to implant normally in the 2nd recipient. Nonperforming assets, such as accounts receivable, are frequently cited as sources of financial difficulty for hospitals. This is best illustrated by a definitive study with diazepam, in which marked prolongation of plasma half-life was accompained by an increase in apparent volume of distribution in the elderly.

klopidogrel lek side effects

Reduction of accounts receivable through total quality management. Polyhydroxyethylaspartamide-spermine copolymers: efficient vectors for gene delivery. Most likely, this phenomenon is dependent upon some minor deviation in descending drive between the cortical level and peripheral motor neuron

klopidogrel lek side effects

We provide functional evidences indicating that caveolin 1 and E-cadherin, deregulated in MTX resistant cells, may play a critical role in cell survival and may constitute potential targets for coadjuvant therapy. Overall, these results indicate that astroglial cells derived from the two midbrain sectors have marked differences in their capacity to synthesize chondroitin sulfate. NIH Consensus Development Panel summary, Cervical cancer screening: the Pap smear.

klopidogrel lek side effects

CDDP is an effective treatment for advanced HCC with portal vein tumor thrombus. The catalytic domain of Escherichia coli K-12 adenylate cyclase as revealed by deletion analysis of the cya gene. Recurrence phenomena after immunoglobulin therapy for snake envenomations: Part 1. Use of protein-interaction maps to formulate biological questions. The umbilical cords of the smaller fetuses in both dichorionic and monochorionic pregnancies exhibited significantly more velamentous insertions and single umbilical arteries than in concordant or mildly discordant twins of similar chorionicity.

klopidogrel lek side effects

Simultaneous measurements of total body potassium and total body water were performed and values of body cell mass and body fat were corrected for physical characteristics. Information on the influence of cutin source and pH on the induction of cutinolytic esterase activity during saprophytic growth of strains from MPV demonstrates that the gene is regulated differently from that in MPVI. The data demonstrated that the aqueous and ethanol fractions of Angelica keiskei did not induce acute toxicity in the skin of the animals, as assessed by anatomical and pathological observations. Psychotropic drug prescribing in a family medicine residency program. The versatility of sol-gel chemistry enables us to manipulate the characteristics of material required for particular applications.

klopidogrel lek side effects

Using a double sheath resectoscope the device is solely connected to the irrigation system. Trypsin, a neutral protease, enhanced the direct plaque response of T cell-suffiecient mouse spleen cell cultures to sheep erythrocytes (SRBC) and significantly increased the number of spontaneous PFC against SRBC in cultures without antigen. A comparative clinicopathologic study of endogenous mycotic endophthalmitis: variations in clinical and histopathologic changes in candidiasis compared to aspergillosis.

klopidogrel lek side effects

Moreover, the elderly population presents a number of problems to the clinician prescribing antiarrhythmics, such as drug accumulation, low compliance and proarrhythmias. Homozygosity mapping of spinocerebellar ataxia with cerebellar atrophy and peripheral neuropathy to 9q33-34, and with hearing impairment and optic atrophy to 6p21-23. Arterial blood-gas and pH changes during the procedure were evaluated. In patients with a mediastinal mass and neurobehavioral deficits, KS should be suspected. The IgG Ab subclass responses were predominantly IgG1 followed by IgG2b for the 50-microg p.o.

klopidogrel lek side effects

Sixteen sera from 14 controls, 18 sera from 15 patients with moderate generalized MG, and seven sera from seven patients on alternate-day prednisone therapy (six with severe generalized MG, one with myasthenic syndrome) were tested by this method. Depending on the changes, they are predicted to lead either to decreased or an increased gene expression.

ticagrelor versus clopidogrel in patients with acs

  • ticagrelor versus clopidogrel in patients
  • clopidogrel child dosage for amoxicillin
  • clopidogrel bisulfate with atorvastatin and aspirin capsules vs tablets
  • site of action of clopidogrel side
  • clopidogrel mechanism of action pubmed search
  • clopidogrel mode d action
  • clopidogrel side effects tinnitus
  • clopidogrel resistance presentations for kids
  • drug eluting stent clopidogrel surgery for spinal stenosis
  • clopidogrel side effects bruising after giving
  • nabratin clopidogrel 75 mg precio
  • clopidogrel aspirin brands india
  • asa vs clopidogrel
  • clopidogrel and ppi interaction fdating
  • clopidogrel 75 mg generico
  • clopidogrel indications and contraindications for epinephrine
  • price clopidogrel bisulfate
  • clopidogrel mechanism of action wikipedia
  • clopidogrel dosage forms ppt
  • clopidogrel bisulfate tablets 75 mg
  • ticagrelor versus clopidogrel in patients with acute coronary syndromes intended for non-invasive
  • mechanism of action of clopidogrel as anti platelet vs anticoagulant
  • platelet function assay clopidogrel tablets
  • prasugrel vs clopidogrel nejm
  • antiplatelet effect of clopidogrel
  • clopidogrel indications and contraindications of ultrasound
  • mechanism of action of clopidogrel bisulfate tab
  • stent farmacologico clopidogrel generic
  • clopidogrel and aspirin tablets 325
  • clopidogrel and ppi interaction fda jobs
  • klopidogrel lek side effects
  • mechanism of action of clopidogrel on platelets
  • clopidogrel plus aspirin tablets content
  • ticagrelor vs clopidogrel in patients with
  • clopidogrel bisulfate generic apotex
  • clopidogrel side effects headache on top
  • clopidogrel 75 mg tab teva tablets
  • price clopidogrel bisulfate generic
  • prasugrel effient vs clopidogrel plavix mechanism
  • ppi and clopidogrel mhra uk
  • clopidogrel metabolism cyp3a4 drug
  • indication for aspirin and clopidogrel versus
  • pharmacological classification of plavix clopidogrel
  • clopidogrel dose post stroke pain
  • asa and clopidogrel interaction with omeprazole
  • ticagrelor versus clopidogrel acute coronary syndromes powerpoint
  • zyllt clopidogrel medication
  • clopidogrel form 1 vs form 2
  • bissulfato de clopidogrel 75 mg efeitos colaterais do rivotril
  • mechanism of action of clopidogrel plavix use
  • ticagrelor vs clopidogrel pharmacokinetics of aspirin
  • clopidogrel brand name in pakistan halal food
  • va pbm clopidogrel medication
  • genetischer polymorphismus clopidogrel medication
  • clopidogrel 75 mg prospect
  • arznei telegramm ticagrelor vs clopidogrel
  • pfa test clopidogrel generic
  • prasugrel vs clopidogrel diabetes insipidus
  • clopidogrel bisulfate ip monograph drug
  • triflusal vs clopidogrel plavix
  • sirolimus stent clopidogrel tablets
  • mode d action du clopidogrel bisulfate
  • atorvastatin 10 mg clopidogrel 75 mg
  • clopidogrel 75 mg generico de protopic
  • ticagrelor versus clopidogrel in patients with acs
  • apo-clopidogrel 75 mg side effects
  • prasugrel vs clopidogrel pptx
  • clopidogrel al 75 mg filmtabletten medicine
  • prasugrel vs clopidogrel in pci
  • action of aspirin and clopidogrel vs aspirin
  • clopidogrel first pass metabolism image
  • fda statement on clopidogrel and ppi
  • clopidogrel 75 mg uson
  • clopidogrel and aspirin tablets ingredients
  • most current information on clopidogrel
  • aspirin plus clopidogrel brands hatch
  • clopidogrel down ng tube

price clopidogrel bisulfate generic

One is led to believe in the heterogeneous nature of the endocrinological response. We have developed a novel silicon-based microfluidic device, multinozzle emitter array chip (MEA chip), as a new platform for small-volume proteomics using liquid chromatography-nanoelectrospray ionization mass spectrometry (LC-nanoESI-MS).

antiplatelet effect of clopidogrel

Additionally p less than 0.125 in binomial-two-sample-tests was accepted. Outcome parameters included: rates of return of spontaneous circulation (ROSC), emergency department admission, hospital admission and hospital discharge. Effects of adrenalectomy and thyroidectomy on in vivo action of glucagon in brown adipose tissue. A 32P-postlabeling method for simultaneous detection and quantification of exocyclic etheno and propano adducts in DNA. Inflammation reaction of the surgical site in the test group was milder than that of the controls 2 weeks after surgery.

asa vs clopidogrel

However, with better targeting and appropriate randomised controlled trials, this area may soon yield important therapeutic strategies to optimise GI health. The ultrastructure of the dark cells and wall cells in the vestibular apparatus of the healthy guinea pigs (21 ears) and disordered guinea pigs (12 ears) were observed using transmission electron microscopy. Operations performed in 991 female patients were compared with those performed in 1485 male patients. In a large number of patients conductive deafness due to eustachian tube dysfunction has been found. The aim of this study was to evaluate the relationship between a panel of biological markers (p53, Bcl-2, HER-2, Ki67, DNA ploidy and S-phase fraction) and clinical-pathological parameters and its impact on outcome in non-small cell lung cancer (NSCLC).

clopidogrel brand name in pakistan halal food

Cases are presented showing the safety and effectiveness of the ISK. Learned pain is a distinct entity with its own set of symptoms, diagnostic criteria, and treatment methods.

clopidogrel resistance presentations for kids

The remaining varicoceles were probably the result of incompetence of other venous tributaries of the spermatic cord and were associated with higher sperm densities. Endogenous cell surface lectin in Dictyostelium: quantitation, elution by sugar, and elicitation by divalent immunoglobulin. The spores have a very thick wall consisting of a thin dark outer layer and a double light inner layer the outer part of which is very wide and often irregular.

clopidogrel dosage forms ppt

Concomitant changes in fetal ChBF were unrelated to arterial oxygen content. Vitamin D nuclear receptor mediates the genomic actions of the active form of vitamin D, 1,25(OH)2D3. Republican-led Congress will take a new approach to healthcare reform.

prasugrel effient vs clopidogrel plavix mechanism

One can conclude that mothering as an essential component of family life will not be abolished. A retrospective study was performed by searching patients with keratomycosis diagnostic on the corneal ulcers database. In addition, FGF2-mediated targeting permits a higher level of transgene expression and in vivo efficacy.

mode d action du clopidogrel bisulfate

Potentiation of diffuse lung damage by oxygen: determining variables. Progression of kidney disease in moderately hypercholesterolemic, hypertensive patients randomized to pravastatin versus usual care: a report from the Antihypertensive and Lipid-Lowering Treatment to Prevent Heart Attack Trial (ALLHAT).

stent farmacologico clopidogrel generic

The Authors have conducted some research on the action of Sulpiride in animals which had been previously obliged to search into the gastric lesion caused by the compulsion. An esophageal atresia was found after delivery, in addition to the prenatally diagnosed duodenal atresia.

mechanism of action of clopidogrel bisulfate tab

The frequencies of responders to recombinant proteins containing the DII were higher than the others and similar to the ones observed against the PvAMA-1 ectodomain. Synovial tissues were collected from DA and DA.F344(Cia5d) rats 21 days after the induction of PIA. Chronic exposure of hepatocytes to reactive nitrogen species (RNS) following liver injury and inflammation leads not only to functional and morphological alterations in the liver but also to degenerative liver diseases and hepatocellular carcinoma.

fda statement on clopidogrel and ppi

Binding to Rac1 induces a dramatic stabilization in SptP of a four-helix bundle that makes extensive contacts with the Switch I and Switch II regions of the GTPase. Typically, a chemical or other stimulus is detected by the periplasmic sensor domain of a transmembrane histidine kinase sensor, which in turn relays a signal through a phosphotransfer cascade to the cognate cytoplasmic response regulator. This finding supports the theory that the anomaly is caused by abnormal remnant tissue originating from the cloacal membrane, which tracks the allantois duct caudally along with fetal longitudinal growth. The dynamics and location of axonal transport blockade by acute intraocular pressure elevation in primate optic nerve.

arznei telegramm ticagrelor vs clopidogrel

Shortening of the time of irradiation and the interval between termination of gamma-therapy and the operation should be regarded the principal advantage of the concentrated irradiation technic. Chronic bronchitis and asthmatic syndrome in the adult population of Cracow during a 5-year observation period Experience with two different medicated intrauterine devices: a comparative study of the Progestasert and Nova-T. While mitral valve prolapse may be complicated by serious ventricular arrhythmias, sudden death, endocarditis, or sudden or progressive mitral regurgitation requiring valve replacement, it is frequently asymptomatic and is usually associated with a relatively benign prognosis. Ease of formation suggests that such units would have arisen early in primondiae organic evolution.

prasugrel vs clopidogrel nejm

Localization of neurons innervating edible snail columellar muscles Isolation of type-C viruses from the Asian feral mouse Mus musculus molossinus. Serotonin alone produced only occasional mild changes in muscle. This study examines for the first time, whether there are significant differences in mean blood pressure levels between a high and a low barium community.

clopidogrel bisulfate with atorvastatin and aspirin capsules vs tablets

The Combined Programs in Medical Technology at the University of Nebraska Medical Center is presented as a model affiliation emphasizing individual program autonomy while contributing the strengths of each to the consortium. Heparin-von Willebrand factor binding as assessed by isothermal titration calorimetry and by affinity fractionation of heparins using synthetic peptides. This may give a clue to design duplex-binding ligands and be helpful for understanding biological activities of these alkaloids. Plasma catecholamines after endotracheal administration of adrenaline during postnatal resuscitation. The original hypothesis was based on a reduction in semen quality in these patients caused by chronic abacterial prostatitis.

triflusal vs clopidogrel plavix

For feeding and calving, both advantages and disadvantages of housing were identified. Use of the prosthesis made from the amniotic membrane for restoration of the patency of the Fallopian tubes in rabbits

clopidogrel first pass metabolism image

An image matching software was used to match the anatomical landmarks in the DRR and the portal imaging and the displacement of the portals in x, y axis and rotation were noted in the anteroposterior (AP) and lateral images. S100 beta is a calcium-binding protein that is expressed at high levels in brain primarily by astrocytes. Karyologic, morphologic and spectrophotometric study of staff cells in human acute leukosis 1950-69 WERE SIGNIFICANTLY INCREASED IN COUNTIES WITH COPPER, LEAD, OR ZINC SMELTING AND REFINING INDUSTRIES, BUT NOT IN COUNTIES WHERE OTHER NON-FERROUS ORES ARE PROCESSED. The second patient was a 69-year-old man who underwent TACE and ablation for HCC 2 years and 7 months prior to being admitted to our hospital for melena and abdominal distension.

sirolimus stent clopidogrel tablets

Radiologically, the lesion is characterized by a lucent defect with marginal sclerosis in the medial metaphysis of the long bone. Subsequently, we compared the DropArray technology with conventional microtiter plates in a cell-based protein-binding assay. Ftorafur was, however, clearly less suppressive to both humoral and cell-mediated immunity than was 5-FU.

asa and clopidogrel interaction with omeprazole

Necropsy of patients dying in hospital up to 72 hours after an accident showed that those with obstruction of the airway had less severe injuries than those in whome no such obstruction could be found. Interventions included nicotine replacement therapy (NRT), bupropion, varenicline, placebo (PLA), or combined NRT and bupropion, and five modes of group and individual behavioral therapy.

klopidogrel lek side effects

Results showed that the oldest Tagus salt marsh population presented higher annual belowground biomass and N productions, and a slower decomposition rate for litter, contributing to the higher N accumulation in the sediment, whereas S. The role of histones in the regulation of transcription is discussed on the basis of the results obtained by the authors and literature data. Given existing market conditions and the prevailing political winds, it is likely that managed care participation will become increasingly important to physicians and physician groups in the years ahead. Concerning 8, in everyday practice most commonly used antibiotics, by means of regression trend line analysis, it has been stated that in the period of 1966-1975 years Staphylococci originating from osteomyelitic patients show a decreasing resistancy to antibiotics examined.

clopidogrel down ng tube

Thermostability is a key feature for commercially attractive variants of the fungal enzyme phytase. Production, selection, and maturation of thymocytes with high surface density of TCR. In parallel to the routine batch potency test in mice, the beta- and epsilonantitoxin levels in 523 samples were estimated in the ELISA procedures. Adrenocortical carcinomas are rare and aggressive malignant tumors, with an incidence of 1 to 2 cases per million inhabitants. The GST-fused fos bZip region was allowed to form a heterodimer with the bZip domain of c-jun, to which radiolabeled AP-1 nucleotides were added.

asa vs clopidogrel

We compared bed linen contamination rate and acquisition rate of MDR-AB with those of MRSA and analyzed the correlation between weekly colonization pressure adjusted by degree of bed linen contamination (WCPe) and weekly acquisition rate (WAR) of MDR-AB. These results suggest that site-specific phosphorylations of LAP modulate transactivation of its target genes. We report findings from a clinical trial evaluating the effects of miglustat treatment in patients with stable type 1 Gaucher disease after enzyme therapy.

 Show Hide 
clopidogrel side effects tinnitus 2018-06-25

The animals then received ethanol by gastric intubation, in doses of 1.5 g/kg every 8, 12 or 24 h, for a period dose of acyclovir in encephalitis pathophysiology of 5 weeks. Bone histomorphometry in patients with chronic renal failure: effect of 1alpha-hydroxyvitamin D3. Low-grade liquid silicone injections as a penile enhancement procedure: Is bigger better?

prasugrel vs clopidogrel diabetes insipidus 2018-03-31

Among patients without pneumonia, however, CIE lacks specificity. Senior medical students as patient-preceptors to introduce basic history and physical examination skills ciproxina suspension bayer to second year medical students. The presence of Fucus increased survival but hindered growth of small (15 mm TL) limpets, which were negatively affected by the presence of large limpets (31 mm TL). Downstream targets of heterogeneous nuclear ribonucleoprotein A2 mediate cell proliferation.

ticagrelor versus clopidogrel in patients 2016-10-14

However, limited work has been done to establish the changes in material properties alprazolam side effects with harmonica of mechanically-responsive cells that experience external stimuli. This study may provide an impetus for more diligent case finding of OSA before operation. The INAS count denotes the number of nonataxia symptoms in each patient. Vascular factors in pathogenesis and therapy of primary chronic polyarthritis

ppi and clopidogrel mhra uk 2010-07-06

Zooming in and zooming out of the attentional focus: an FMRI noacid 20 mg study. A large F(2) population was used to integrate the existing genetic maps around BnMs5.

bissulfato de clopidogrel 75 mg efeitos colaterais do rivotril 2018-10-05

It is recommended metronidazole antibiotic classification that faculty members and research administrators consider the needs and requirements of education and plan the researches in education according to these priorities. Lateral ventricle choroid plexus papilloma in childhood: management and complications.

mechanism of action of clopidogrel plavix use 2019-07-23

During the period from 2 days to 2 weeks following HHK implantation, Schwann cells were found to undergo dedifferentiation and proliferate along the HHK implant. Therefore, there is a great interest in developing strategies to treat infarcted CMs that are able to regenerate cardiac tissue and promote revascularization of infarcted zones in the heart. The CMI against Streptococcus sanguis strain 2A, streptococcus pyogenes strain M5, and AHOM was significantly increased in inactive and active RAS. Chest roentgenology and angiography of the ischemic heart disease. The acic tablets vaikams filmukai implications of these findings for child placement policies are discussed.

prasugrel vs clopidogrel nejm 2017-06-22

A questionnaire to five groups elicited values regarding the relative importance of ten components. Effect of rutin and hyaluronidase on the allergic-hypergic inflammation of the skin and joints Severe histamine mediated reactions to intravenous drugs used in anaesthesia may occur as a result of anaphylactic and anaphylactoid reactions. Among the jumex deprenyl selegiline hcl side new theoretical constructs emerging from Positive Psychology, of particular relevance to the domain of occupational health psychology is the notion of adult resilience.

clopidogrel 75 mg prospect 2010-10-07

Treatment efficacy with bone marrow derived mesenchymal stem cells and minocycline in rats after cerebral ischemic injury. The principle of fenofibrato nome generico the Ayurvedic system is to consider the body as a whole, ailments of different organs not being treated separately as in modern medicine.

clopidogrel brand name in pakistan halal food 2018-06-08

Soft tissue sarcomas are rare malignancies in the head and neck region. Neurochemical and neuroanatomical investigations suggest a key role of the dopaminergic mesolimbic system in these processes. Two randomized household-based trials of zanamivir, an influenza antiviral agent, are analyzed using the proposed methods. Trypan blue cell viability assays and flow cytometric cell-cycle analysis demonstrated that the transfer of both p53 and tranax cipla E2F-2 induced cell death in D-54 MG, a p53-resistant glioma cell line.

ticagrelor versus clopidogrel in patients 2010-06-30

The limit of detection of cadmium is 2.5 mg for the left kidney and 1.8 microgram/g (wet weight) for the liver, for a localized dose of 670 mrem. They can acyclovir adalah sale p untuk luka bakar be stably expressed in p53-null H1299 cells at 39 degrees C, become transcriptionally activated at 32 degrees C, and induce expression of p53-responsive genes MDM2 and p21WAF1.