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Topilex (Topiramate)

Topilex is a medicine called an anticonvulsant. It is used to control and prevent certain types of seizures. It is often used to control and prevent tonic-clonic seizures, also called grand mal seizures. It may also be used to treat partial seizures. You may also hear Topilex called by one of its brand names, Topilex.

Other names for this medication:
Topiramate, Topamax, Epitomax, Letop, Neutop, Piramax, Talopam, Topamac, Topictal, Topigen, Topilex, Topimax, Topina, Topiramato, Topirol, Toplep,

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Amoxydar, Parkopan, Benestan, Blumox, Victrelis, Anabact, Acortiz, Minisec, Levoday, Prospera, Tetracycline, Ezetimiba, Aquacil, Tramazac, Olpress, Lyflex, Blistex, Edenil, Verelan, Flochek, Clavipen, Diazeco, Mutabase, Cardilax, Pinaclav, Ibumax, Vantin, Conmy, Zacpac, Larotid, Winpen, Damicine, Deworm, Emilok, Romparkin, Metrosa, Nevirapine, Amlovasc, Zelapar, Nizoral, Fromilid, Oraz, Rapivir, Novamoxin, Rulid,

Topilex comes as a tablet, a sprinkle capsule (capsule that contains small beads of medication that can be sprinkled on food), and an extended-release (long-acting) capsule to take by mouth. The tablets and sprinkle capsules are usually taken with or without food once or twice a day. The extended-release capsules are usually taken with or without food once a day. Take Topilex at around the same time(s) every day. Follow the directions on your prescription label carefully, and ask your doctor or pharmacist to explain any part you do not understand. Take Topilex exactly as directed. Do not take more or less of it or take it more often than prescribed by your doctor.

There is another medication with a name similar to the brand name for Topilex. You should be sure that you receive Topilex and not the similar medication each time you fill your prescription. Be sure that the prescription your doctor gives you is clear and easy to read. Talk to your pharmacist to be sure that you are given Topilex. If you think you were given the wrong medication, talk to your pharmacist. Do not take any medication unless you are certain it is the medication that your doctor prescribed.

Topilex tablets have a bitter taste so you should swallow them whole. It is especially important that you not take Topilex tablets that have been broken for any length of time because tablets that are broken may lose their effectiveness over time.

The sprinkle and extended-release capsules (Qudexy XR brand only) may be swallowed whole or opened and poured over soft food. Swallow extended-release capsules (Trokendi XR brand only) whole; do not split, chew, or sprinkle on food.

To take the sprinkle capsules or extended-release capsules (Qudexy XR brand only) with food, follow these steps:

  1. Prepare a teaspoonful of soft food such as applesauce, custard, ice cream, oatmeal, pudding, or yogurt.
  2. Hold the capsule upright over the food.
  3. Twist off the top of the capsule and pour the entire contents onto the spoonful of food.
  4. Swallow the entire mixture immediately without chewing.
  5. Drink fluids right after swallowing to wash down the mixture and to be sure that you swallow all of it.

Your doctor will probably start you on a low dose of Topilex and gradually increase your dose, not more than once every week.

Topilex may control your seizures or migraines but will not cure your condition. Continue to take Topilex even if you feel well. Do not stop taking Topilex without talking to your doctor, even if you experience side effects such as unusual changes in behavior or mood. If you suddenly stop taking Topilex, you may have severe seizures, even if you have not had seizures in the past. Your doctor will probably decrease your dose gradually.

Your doctor or pharmacist will give you the manufacturer's patient information sheet (Medication Guide) when you begin treatment with Topilex and each time you refill your prescription. Read the information carefully and ask your doctor or pharmacist if you have any questions. You can also visit the Food and Drug Administration (FDA) website ( or the manufacturer's website to obtain the Medication Guide.

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The percentage of 125I transferred to egg yolk was significantly reduced by the inclusion of high-glucosinolate rapeseed meal but not by low-glucosinolate meal. D2 receptor partial agonists: treatment of CNS disorders of dopamine function. Use of an antibacterial envelope is associated with reduced cardiac implantable electronic device infections in high-risk patients. The model was verified experimentally for a range of model drugs and peptides.

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Checkpoint response plays a more protective role in HZE particle-irradiated cells than in X ray-irradiated cells. The differences were more pronounced in sensory than in motoneurons. The catalytic hydrolysis of p-NPA can be considered a useful probe of conformational states of macromolecules. The control arterial histamine level was 0.041 plus or minus 0.002 mug/ml (mean plus or minus SEM) as determined by a fluorometric assay.

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Our conclusions are based on available evidence, our own experience working with guideline developers, and workshop discussions. Rapid and dose-dependent increases in the plasma bile acid concentrations were observed in rats after a single intravenous administration of troglitazone.

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Since the drug did not interfere with the modification induced by MAD on the adrenal steroidogenesis, as seen by EM studies of the zona fasciculata of the androgen-treated animals, it is likely that it may have exerted its adrenolytic effect on the peripheral vessels of the MAD-induced hypertensive rats. Phytoremediation, given the right choice of plant, may be theoretically applicable to multi-contamination. Eighty subjects--30 migraineurs during the attack, 30 patients in the interictal period, and 20 healthy volunteers--were studied using two technologies for functional assessment: transcranial Doppler ultrasound and magnetoencephalography. Regional replication of the bacterial chromosome induced by derepression of prophage lambda.

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Natural disasters: how to resume operations and prioritize your infrastructure. Whether percutaneous radiofrequency ablation (PRFA) is as effective as repeat hepatectomy for recurrent small hepatocellular carcinoma (HCC) in the long-term remains unknown.

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Rats subjected either to acupuncture or to ginger pharmacopuncture at GV20 demonstrated enhanced spatial memory, and the activities of catalase and glutathione peroxidase in both cerebral cortex and hippocampus were improved. In addition, a decrease in XDH/XO messenger RNA was found by competitive PCR. Measurement of arterial dimensions: review of visual and quantitative angiographic techniques.

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