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Topimax (Topiramate)
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Topiramate

Topimax is a medication that has been available for a long time to treat migraines and seizures. Based on new research findings, Topimax is now being used “off-label,” or outside of its currently approved indications, to treat alcohol dependence. Specific circumstances, which your physician will discuss with you, may make this medication the first-choice treatment option. Exactly how Topimax works in alcohol dependence is not known, but it is thought to reduce alcohol’s pleasurable effects and so helps people to abstain from alcohol.

Other names for this medication:
Topiramate, Topamax, Epitomax, Letop, Neutop, Piramax, Talopam, Topamac, Topictal, Topigen, Topilex, Topimax, Topina, Topiramato, Topirol, Toplep,

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Topimax is used alone or with other medications to treat certain types of seizures including primary generalized tonic-clonic seizures (formerly known as a grand mal seizure; seizure that involves the entire body) and partial onset seizures (seizures that involve only one part of the brain). Topimax is also used with other medications to control seizures in people who have Lennox-Gastaut syndrome (a disorder that causes seizures and developmental delays). Topimax is also used to prevent migraine headaches but not to relieve the pain of migraine headaches when they occur. Topimax is in a class of medications called anticonvulsants. It works by decreasing abnormal excitement in the brain.

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In this review, we highlight current advances on the mechanisms of how Sema3E-Plexin-D1 interaction shapes the networks of multiple biological systems, in particular the vascular and nervous systems. If a curvature cannot be controlled satisfactorily, however, surgical fusion may be indicated earlier than desired. Mycobacterium kansasii-induced death of murine macrophages involves endoplasmic reticulum stress responses mediated by reactive oxygen species generation or calpain activation.

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This report describes a case of reverse flow in the umbilical vein and ductus venosus during atrial contraction of a fetus at 12 weeks of gestation with increased nuchal translucency (9.1 mm). The mechanism of amphotericin-induced distal acidification defect in rats. To examine the mRNA expression of the linker for activation of T cell (LAT) and its upstream regulatory factors (Syk, Lck and ZAP-70) in the peripheral blood T cells of asthmatic patients. Pargyline undergoes metabolic N-oxidation in rat and rabbit liver microsomal preparations. In this article, we discuss the domain structure of Zizimin proteins from an evolutionary viewpoint.

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Application of a systemic insecticide by trunk implantation to control a mealybug vector of the cacao swollen shoot virus. This is to enable examination of the cell morphology and the polysaccharide and lipoid histochemistry of the cells and the dried liquid phase. Already on the day of admission, raised elimination rates of sICAM-1 were found in the urine of patients who had developed an ARF.

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Currently, southern Karelia can be considered as a zone of sympatry for I. Improved medium for selective isolation and enumeration of Bifidobacterium. In other fMRI scans, a straight-leg raising procedure is performed to exacerbate the back pain. Based on the mode of presentation and clinical findings along with an understanding of lung embryology, one can develop a thorough differential diagnosis that allows for the evaluation of the lesion in question.

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In this study, we have developed novel derivatives of Deferiprone with increased anti-parasitic activity and reduced cytotoxicity against human cell lines. A methodology for meeting context-specific information needs related to nursing orders.

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When melanocyte extracts were treated with glycopeptidase F, a approximately 44 kDa band appeared. Accuracy in prediction of catheter rotation in IVUS with feature-based optical flow--a phantom study. Randomised trials relevant to mental health conducted in low and middle-income countries: a survey.

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To ascertain the level and quality of audit activity among junior doctors, their attitudes to audit, and their views on its educational value. Physical evidence for the dimerization of the triphosphopyridine-specific isocitrate dehydrogenase from pig heart. An acute aplastic crisis usually occurs shortly after viral infection, however, viral serologies are usually negative and the pancytopenia is often fatal if left untreated. The binding of furosemide to serum proteins in elderly patients: displacing effect of phenprocoumon.

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In this hypothesis, the induction of neoplasia is envisaged as embodying (a) initiation of preferentially partly-differentiated and resting stem cells and (b) promotion of the initiated cells, through mitosis and further differentiation and by adaptations of normal ontogenic mechanisms, into a variety of novel phenotypes which are malignant or potentially so. dose of cyclophosphamide, underwent colocystoplasty, underwent each technique or served as controls. This result was found for all four investigated anxiety disorders.

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The Tonsil and Adenoid Health Status Instrument is a valid, reliable, and sensitive instrument with 6 distinct subscales. Sequestration of adenoviral vector by Kupffer cells leads to a nonlinear dose response of transduction in liver. New approaches to hyaline membrane disease have emerged in recent years. Isolation of Japanese encephalitis virus from mosquitoes collected in Bankura district (West Bengal) during October 1974 to December 1975. Relationship between penile thermal sensory threshold measurement and electrophysiologic tests to assess neurogenic impotence.

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The development of the ophthalmoscopic aspects of patients during hemodialysis treatment 100 intravenous infusions of Corynebacterium parvum were given to thirty-six patients at a dose of 5 mg/m2. Mono- and polysynaptic connections between identified neurons in the system of the passive avoidance reflex of the snail.

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Respiration rates and citrate synthase activity demonstrated power regression versus tissue weight with regression coefficients -0.231 and -0.170, respectively. Such studies would further contribute to the evaluation of anxiety and depression as risk factors for hypertension. An association between EFA deficiency and altered fatty acid composition of pulmonary surfactant phospholipids is suggested. Because of their advantageous position, home care nurses can be instrumental in addressing this problem. Nodular lymphoid hyperplasia - a rare case of lymphoproliferative disorder of the lungs

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Redistribution and abnormal activity of phospholipase A(2) isoenzymes in postinfarct congestive heart failure. This depression of blood flow response by blunt trauma prompts further investigation of the role of vascular factors in delayed union. Rearrangement of the bcl-6 gene correlated with a favorable clinical outcome in DLLC and may thus serve as a prognostic marker in patients with this form of malignant lymphoma. In spite of daily plasma exchanges, he died 10 days after exposure. The efficiency of deep mucus entry was also low with a slow pH decrease as seen in pH profiles simulating the situation in babies.

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The review summarizes the present state of the involvement of relatively small computing devices in the collection and processing of gamma-ray spectrum data. In the proposed scheme, a genetic algorithm (GA) is used for the feature selection and the conjugate gradient (CG) method for the parameter optimization. The surgical approach required for patients diagnosed in the first or second trimester was less clear. Observations on the relation between alcohol absorption and the rate of gastric emptying.

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prolixus, (2) if this modulation is a general one or it is specific for each type of volatile, and (3) if it is controlled by exogenous or endogenous mechanisms. A 5 day pretreatment period began 2 days after hypophysectomy at 21 or 24 days of age. These neuroanatomic dissections provide a basis for surgical modifications that may address a variety of concerns regarding urinary continence in female surgical patients. Within the intrinsic amygdala, regions were determined that are essential for network integrity.

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The obtained results showed only a percentual, but not statistically significant improvement. One carrier, through severe social withdrawal, showed overreaction to the possibilities of disease transmission. Effect of 6-azauridine on de novo pyrimidine biosynthesis in cultured Ehrlich ascites cells. Comparison of color flow imaging and peripheral venous saline contrast during transesophageal echocardiography to evaluate right-to-left shunt at the atrial level.

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The activities of beta-glucuronidase, arylsulphatase A and acid DNAase were measured in homogenates from Kupffer cells and hepatocytes prepared from germ-free, monocontaminated and conventional rats. Cancer therapy utilizing cellular immunity has been developed using various reagents including stimulus for innate immunity, cytokines, vaccines, autologous cells and gene-vectors. The methionine residues in bovine growth hormone were chemically modified wih chloramine-T at pH 7.4 using different chloramine-T methionine molar ratios. Starting from a recent clinical case, we present the different causes of rectal prolapse and their specific treatments.

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Syndrome resembling disseminated lupus occurring during apresoline therapy. The suprachiasmatic nuclei are involved in determining circadian rhythms during restricted feeding.

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Bone age appeared to be advanced in pubertal IVF-conceived girls, but not in boys, compared with controls. Reliability study and cross-sectional analysis of hip strength and functional performance.

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The reaction layer was not obvious by the metallographic examination. However, deviant targets elicited enhanced N2 and P3 components for targets with explicit knowledge but a larger N2 effect for targets with implicit knowledge, revealing that implicit knowledge expresses itself in relatively early components (N2) and explicit knowledge in additional P3 components. Indirect ELISA and Western blot assay showed that the four mAbs specifically recognized the Norovirus capsid protein expressed in E.coli. Spreadsheet software program to analyse costs beyond drug acquisition price. The relationship of glycogen and glucose to anaphylactic histamine release from chopped sensitized guinea pig lung in vitro was studied.

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The conjugation junction structure appears during the initiation of conjugation development, and disappears during the exconjugant stage. Crystal structure of glucose dehydrogenase from Bacillus megaterium IWG3 at 1.7 A resolution. Its signal intensity and contrast enhancement were similar to those of the primary tumour.

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Potential microbial (anaerobic and aerobic) as well as physicochemical processes as feasible remediation technologies to combat environmental pollution are being explored. The information to underpin the consideration of the topic of the healthcare audit must be consistent, contemporary, complete and correct information.

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Dynamics of modifications of irritability of the cerebral cortex before and after convulsive seizures Vaccine A, prepared with galactose, was more readily identified in the stool specimens of its recipients and was more likely to provoke an O antibody response than was vaccine B. (2004) model (Journal of Advanced Nursing 48, 84): (1) problem definition, (2) accumulation of building blocks for intervention design, (3) intervention design and (4) intervention validation. The 12 tumours tested were obtained from three different monkey species inoculated with Herpesvirus saimiri or herpesvirus ateles.

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The vigilo-somnograms showed after the injections a change in the EEG-stages, indicating a reduction of alertness, transitions into reduced wakefulness or beginning stages of sleep. A young man who had a long history of sinusitis developed subarachnoid hemorrhage and died. 1 By means of the double sucrose-gap technique, the effects of bradykinin and the bradykinin potentiating peptide BPP(5a) were compared on the guinea-pig taenia coli under a number of experimental conditions.2 In normal Krebs solution the response to bradykinin was mostly a slight stimulation, characterized by a depolarization, an increase in spontaneous spike activity and a contraction.

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We review the technical approaches currently available (differential display, complementary DNA microarrays), to identify novel genes involved in the determination of cell fate. Nano-electrospray ionization time-of-flight mass spectrometry of gangliosides from human brain tissue.

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Scientific communications have two main forms, oral presentation at scientific meetings, accompanied by audio-visual aids, and manuscripts prepared for publication in scientific journals. When azastene (4, 4, 17 alpha-trimethylandrost-5-eno (2,3-d) isoxazol-17-ol), an inhibitor of gonadal and placental 3 beta-hydroxy steroid dehydrogenase conversion of pregnenolone to progesterone in rhesus monkeys, was added to the culture medium at a concentration of 0.3-150 mumol/l, no marked effect on the secretion of progesterone was observed.

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From the data obtained it is concluded, that BLM inhibits growth of Rous Sarcoma Virus by blocking cell proliferation. In adult settings of angiogenesis, as in tumors or in the female reproductive system, the endothelium of a subset of new vessels strongly expresses ephrin-B2, once again contrary to earlier views that such new vessels lack arterial/venous characteristics and derive from postcapillary venules.

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WNT ligands bind to Frizzled receptors and co-receptors (LDL receptor-related protein 5/6), triggering a cascade of signalling events. Nevertheless, the harmful health effects of tobacco use are well documented, including greatly increased risks of developing chronic obstructive pulmonary disease, cardiovascular disease, and many forms of cancer. The findings strongly suggest that the inhibitors of JNK, Erk1/2, or antioxidants may be exploited for prevention of Cd-induced neurodegenerative diseases. Role of lipid peroxidation and of various antioxidants in the pathological process in burns and the effect of alpha-tocopherol on their course A strain deleted for the ptsGHI genes was transformed with plasmids expressing either the wild-type ptsH gene or various S46 mutant ptsH genes (S46A or S46D).

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Medical workers in the political processes of the period of revolutionary populism (the 60s and 70s of the 19th century) Homology modeling of nematode Caenorhabditis elegans CED3 protein-inhibitor complex. However, possibly because of the immune-privileged character of the CNS, the spontaneously evoked physiological activities of both macrophages and T cells in the CNS are restricted, and appear to need well-controlled boosting in order to be effective.

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Effects of prolactin (PRL) on pituitary and testicular function in mice with hereditary PRL deficiency. There was no apparent difference in survival by topotecan dose schedule.

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Transforming the contrast values into a relative decibel scale shows that this increase in latency occurs at significantly higher relative contrast values under scotopic as compared with photopic conditions. Use of the Internet by patients: not a threat to nursing, but an opportunity? Impact of comorbid conditions on survival in endometrial cancer. Proteins do not pass through the junctional complexes into the intercellular spaces under physiological conditions but may do so in very early embryological stages or if the luminal hydrostatic pressure is experimentally increased. Adequate management of gimalxina review times fever and the malaria often associated with it requires understanding the perceptions and representations of parents, which will make it possible to learn the true proportion of malaria in fevers in the two villages and thus to apply appropriate strategies.

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Suppression of HER3 expression by RNA interference reduces melanoma cell proliferation, migration, and invasion in vitro. The present findings support the hypothesis that EDS-treated rats can serve as a model for studying the LC development in the prepubertal testis and indicate a specific role of hormonal factors like INSL3 in this process. The marked complexity of the TCR V delta 2 junctional sequences and the oligoclonality of what is indomethacin 75 mg sr capsules empty the TCR V delta 2 genes in the control subjects are indicative of a positive selection and expansion of specific T cells in the normal, healthy condition. Ultra-compact photonic crystal waveguide spatial mode converter and its connection to the optical diode effect. Computerized tomography of the brain showed marked hypodensity of the subcortical white matter.

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Peer victimisation and internalising difficulties: The moderating role of friendship quality. Some aspects of the work of Robert Brown and the investigator naturalists in Madeira during August 1801. Further supporting the idea that Shh is required for the in vivo establishment of early oligodendrocyte populations, expression of PDGFR(alpha) can be partially rescued by virally mediated expression of Shh in the Nkx2.1 mutant telencephalon. Evidence-based recommendations for PISA measurements in bactiver suspension para la diarrhea in dogs mitral regurgitation: systematic review, clinical and in-vitro study. The bigger half was regarded as the antero-medial (AM) bundle, and the remaining half was regarded as the postero-lateral (PL) bundle.

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Diagnostic potential of amlodipine besylate side effects webmd drugs an iron-regulated hemin-binding protein HbpA that is widely conserved in Leptospira interrogans. FcRgamma represents the Fc receptor gamma chain whereas FcgammaR means the Fc receptor for IgG. The racial integration of medical and nursing associations in the United States. Employer health coverage for domestic partners--identifying the issues. Crucial residues for oligomerisation of AsGFP(499) were predicted and selected for mutation.

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It was hypothesized that thoracic epidural anesthesia on the day after a thoracotomy could block azithromycin 250 mg treatment side effects inhibitory neural pathways and increase the shortening of costal and crural diaphragmatic segments. If patient participation is to be more widely incorporated into outpatient primary care, it must be addressed within the complexity and multiple demands of community practice. Influences of diet on tumor growth in man have not yet been observed up to now. The population of adults with congenital heart disease (ACHD) now exceeds that of children with congenital heart disease.

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Inhibitory effect of cortisone hyperlipemia on arterial lipid deposition in cholesterol-fed rabbits. However, we studied the fragmentation of protonated AAs using a single quadrupole mass spectrometer. Recently, we demonstrated that activated tramadol round yellow pill protein C (APC) can lessen the severity of spinal cord injury (SCI) in rats during the acute and subacute phases.

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The change in shape of buy finpecia canada 3T3 and L929 cells due to Bt2cAMP treatment is accompanied by altered intracellular distribution of microfilaments and microtubules. Studies in men are not consistent regarding the effects of thyroid hormone on the production of gonadotropins. Specifically, the potential errors that result from comparing group means are shown. Daghestan contains many distinct populations characterized by different degrees of isolation, ethnic backgrounds and ecological conditions. The highest IgG serum levels were observed for whole bee venom followed by phospholipase A.

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