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Topina (Topiramate)
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Topiramate

Topina is a seizure medicine, also called an anticonvulsant. Topina is used to treat seizures in adults and children who are at least 2 years old. Trokendi XR is for use in adults and children who are at least 6 years old. Extended-release Topina has a higher minimum age (at least 10 years old) when used as the child's only seizure medicine. Some brands of Topina are also used to prevent migraine headaches in adults and teenagers who are at least 12 years old. These medicines will only prevent migraine headaches or reduce the number of attacks, but will not treat a headache that has already begun.

Other names for this medication:
Topiramate, Topamax, Epitomax, Letop, Neutop, Piramax, Talopam, Topamac, Topictal, Topigen, Topilex, Topimax, Topina, Topiramato, Topirol, Toplep,

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Pritor, Spirotone, Anazol, Hexymer, Losartan, Trak, Entizol, Nidazol, Abloom, Akarin, Ponstil, Candistat, Taucaron, Asquam, Sarotex, Cardensiel, Madol, Uroxal, Esopral, Dumocycline, Gabatal, Obelit, Olmetec, Anzo, Tryptizol, Brux, Ezedoc, Zoloft, Organosol, Allopurinol, Noprose,

Topina is used alone or together with other medicines to help treat certain types of seizures (eg, partial seizures, tonic-clonic seizures, or Lennox-Gastaut syndrome). This medicine will not cure epilepsy and will only work to control seizures for as long as you continue to take it. It is also used to help prevent migraine headaches.

This medicine is available only with your doctor's prescription.

This product is available in the following dosage forms:

  • Capsule, Extended Release
  • Tablet
  • Capsule

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This was not due to a lowered capacity of the pituitary to synthesize and secrete ACTH since peptide levels following adrenalectomy did not reveal age differences. Proliferation and accumulation of mitochondria in one part of the cell and deeply indented nuclei were frequent. Supraventricular tachycardia that mimics ventricular tachycardia.

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Our purpose was to investigate whether markers for activation of the immune system are present in patients with preeclampsia by assessing maternal plasma and amniotic fluid for tumor necrosis factor-alpha and interleukin-1 beta. This is due to a coating of bacterial surfaces by substances such as algal products having a protective effect as demonstrated in experimental studies by the authors.

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We provide an overview of cytoskeletal components underlying INM in different systems, discuss current understanding of its kinetics and timing, and evaluate how conflicting results could be explained through developmental and evolutionary considerations. Glycocholate and other bile acids inhibit the response of isolated hepatocytes to phalloidin in a concentration dependent manner. Intravitreal injection of human CFH resulted in the suppression of formation of new, and regression of preformed laser-induced CNV in the rat model. Macroscopic lung tumour nodules were not observed by 7 days after tumour challenge. Growing up with HIV/AIDS: a study on adolescents with HIV/AIDS and their family caregivers.

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We earlier showed that carboxylated N-glycans expressed on receptor for advanced glycation end products (RAGE) and other glycoproteins mediate colitis through activation of nuclear factor kappa B (NF-kappaB). The results of this study show that under specific conditions the ATPase activity of Zajdela hepatoma mitochondria can be stimulated by uncouplers. The main therapy relies on selective beta-agonists in combination with steroids. The networks of women in abusive relationships were smaller in size, but more efficient in their ability to reach their members, than those of nonabused women.

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The effects of different analgesic regimens on transcutaneous CO2 after major surgery. Treatment of diabetes insipidus complicated by diabetes mellitus with chlorpropamide and clofibrate. Then after sharp dissection to the clavicle, blunt dissection was performed to the pedicle to allow the flaps to be able to cover the wound after rotation without undue tension. Serial nasal specimens were obtained from all household members over at least eight days and tested quantitatively by qRT-PCR for the influenza virus (sub)type of the index patient. Dose-response lines for the tail-flick and hot plate tests were obtained in rats which had received systemic injections of morphine (10-150 mg/kg i.p.) and intracerebroventricular (i.v.t.) injections of naloxone (3-20 micrograms).

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On the basis of such a pathogenesis, various possible prophylactic and therapeutic measures and their organizational requirements are significant. Solubility profiles of these aerosols were determined by performing in vitro solubility tests over 100 d in a simultant solution of the extracellular fluid. Nucleoli are not evident in erythroblasts whose nuclei indicate cells in the latter stages of development. The movements noted by the woman were correlated to those recorded by a fetal movements recorder.

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Medication adherence is critical in Tuberculosis (TB) treatment success, but existing tools are inadequate in identifying non-adherents, reasons for non-adherence or interventions to improve adherence. There was no significant correlation between body cathexis and achieved knowledge. Hence, these results should be considered when long-term peri-pubertal GnRHa treatment is used in children.

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Cyclin Es is the first splice variant of a cell cycle regulatory protein to be described. Fluorescence studies confirmed biotinylation of cellulose nanowhiskers and binding of cellulose nanowhiskers to biotinylated microtubules. The main intersystemic anastomoses are situated in the superficial ventral muscles, and the intrasystemic ones--in the superficial dorsal muscles, trachea and esophagus. Histopathology showed adequate proximal and distal resection margins with an average lymph node yield of 25 nodes (range 16-30 nodes). Rate of change of halothane concentration in a large animal circle anesthetic system.

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Effects of beta-adrenoreceptor antagonists on sino-aortic baroreflex sensitivity and blood pressure in hypertensive man. Vitreoretinal and anterior segment surgery through the pars plana: part I. The most interesting compound in this series, the 1-methyl-4-piperidylidene derivative of 1-azaxanthene, shows the profile of an orally effective potent bronchodilating agent as well as a moderate antihistamine. Simian virus 40 DNA from psorospermin-treated cells was shown to contain numerous abasic (apyrimidinic/apurinic) sites. We investigated the patterns of failure and prognostic factors for locoregional control (LRC) in patients with upper urinary tract (UUT) transitional cell carcinoma (TCC) treated with radical surgery to evaluate the role of adjuvant radiotherapy.

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Microlaryngoscopy and microsurgery of the larynx (literature survey) Reversal of ischemic cell injury in hamster trachea and human bronchus by explant culture. Fringe was originally identified as a novel secreted signaling protein with a key role in wing formation of Drosophila.

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Prostaglandin regulation of the sex hormone receptor content in human decidual tissue To examine associations between dietary intakes of total energy, carbohydrates, protein, fats, cholesterol, and sodium and LUTS in men. In amniotes, V2 cells develop in the ventral spinal cord, just dorsal to motoneurons.

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One of the established clones, K1, showed a strong immunoreactivity in the marginal zone at the 19th day of gestation (E19). The presence of cells containing secretin or a secretin-like peptide adds a new cell type to the three already characterized (insulin, glucagon and somatostatin containing cells) in monolayer culture. The corrective actions focused on systems improvement, as opposed to the human error of the memory lapse.

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Policy development will always require a strong government presence in co-ordinating and regulating health care provision, and an NGO sector responsive to the policy goals of government. We therefore undertook a population-based cohort study to determine whether perioperative epidural anaesthesia or analgesia is associated with improved 30-day survival. Admissions of IPA patients under age 65 to ten hospitals are compared with admissions to the same hospital of patients covered by Blue Cross and Blue Shield plans or commercial insurance programs. A prospective, longitudinal study of children registered for adoption.

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The antitumor action of endotoxin was obliterated when higher challenges of tumor cells or solid tumor pieces were used. Individuals with a predisposition to psychotic features tend to display such features during more severe episodes of depression. A diverticulum of the nasolacrimal duct that presented 26 years after nasal trauma is described. Nonassociative explanations of behavioral changes induced by central cholinergic drugs.

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Cholangiocarcinomas display intestinal and pyloric gland metaplasia-cell phenotypes. The classification according to professional groups was carried out correspondingly to an appropriate modification of the professional catalogue of the WHO. The tunneling frequencies were 0.693(55) MHz for C 3H 5 (80)SeH and 0.608(71) MHz for C 3H 5 (78)SeH.

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Anterior-chamber myopic lenses for phakic myopic patients remain controversial. Members of this family can be phosphorylated and activated by the tumor suppressor kinase LKB1, a conserved polarity regulator of epithelial cells and neurons. The postmortem examination on one of these siblings exhibited the dysmyelination in the cerebrum and spongy lesions of the white matter in the cerebellum, pons, medulla oblongata and spinal cord. In our experience, based on 62 posterior fossa tumour operations, insertion of a cerebrospinal fluid (CSF) diverting shunt because of hydrocephalus makes the subsequent tumour excision more difficult and hazardous. One of its demonstrated functions is the retention of incorrectly or incompletely folded proteins, suggesting that calnexin is a component of the quality control system of the endoplasmic reticulum.

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It was hypothesized that NRFR participation in disaster preparedness training was related to the types of organizations and communities in which they performed their duties. In light sleep and awake the middle responses of most subjects gave thresholds more sensitive than the late by 10-15 dB and also fewer indeterminate trials. Results from the clinical pilot and validation studies showed that the SUM8 diary scores were robust and reliable for use as efficacy endpoints in studies of mucoactive drugs. Evidence of HPV DNA was found in only one lesion, which showed HPV type 6-11 by ISH and HPV positivity by Southern blotting of the amplified product after the PCR.

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Paroxysmal and other features of the electroencephalogram in migraine. Quantitative reverse-transcriptase polymerase chain reaction (Q-RT-PCR) and recent advances in genome-wide DNA microarray-based gene expression profiling (GEP) represent powerful tools for the systematic exploration of the molecular variation underlying the biologic and clinical heterogeneity of CN-AML.

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Recognition of multiple antibody epitopes throughout Borrelia burgdorferi p66, a candidate adhesin, in patients with early or late manifestations of Lyme disease. There has been early or late mortality in this group of patients, and postoperative morbidity has been minimal. It consists of a platform suspended by three springs, the damping being provided by a much smaller mass, suspended from the platform by a spring and damped in an oil bath.

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Gas exchange by pods and subtending leaves and internal recycling of CO(2) by pods of chickpea (Cicer arietinum L.) subjected to water deficits. Here, we present a publicly available web application that facilitates a high resolution mapping of measured molecular masses to peptides and proteins, irrespectively of the enzyme/digestion method used. Anatomic variations in intrahepatic bile ducts in a north Indian population. Cytokine production by monocytes, NK cells, and lymphocytes is different in preeclamptic patients as compared with normal pregnant women.

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The glucocorticoid stimulation of mouse mammary tumor virus RNA production in cultured cell lines is the only example to date where such a mechanism is supported by RNA-DNA hybridization studies. Such behaviour is analagous to that observed in all trisomic organisms.

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These results suggest that glucocorticoid hormones might participate in the control of pain by modulating P2X(3) receptor-mediated events in sensory neurons, and the effect is mediated by glucocorticoid receptors and the downstream activation of protein kinase A. The superfusion technique described enables a stimulus synchronous observation of release mechanisms by reason of the size of the perfusion chamber and by the arrangement of the medium supply. The immunodepressive and bone marrow stem cell-reducing activities of imidazole-4-carboxamide,5-(3,3-dimethyl-1-triazeno) (DTIC), an antitumoral agent reported to possess little immunodepressive capacity in man, have been investigated in mice and compared with those displayed by cyclophosphamide (Cy).

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This study compared barriers to employment among disabled and non-disabled youth in South Africa. Genomic and antigenic characterization of the Salehabad virus, a species of the genus Phlebovirus, and four other unclassified phleboviruses (Arbia, Adria, Arumowot and Odrenisrou) demonstrate a serological and genetic relation to one another and are distinct from the eight other recognized species within the genus Phlebovirus. The coat protein profile of the ftsY mutant spores was different from that of wild-type spores.

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Hydration of hydrogentungstate anions at different ph conditions: a car-parrinello molecular dynamics study. Human exposure to complex mixtures of polycyclic organic matter (POM) from the products of incomplete combustion contribute to the potential lung cancer risk in urban areas. Influence of the functioning of the pronephros on the morphogenesis of the primary ureter in the frog embryo We believe that the place of our modification method in incontinence surgery becomes more clearly with the comparison of the other anti-incontinence surgery techniques in patient groups with the same characteristics.

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Interaction of TIM-3 with HMGB1 inhibits the recruitment of nucleic acids to the endosomal compartment of dendritic cells, impairing the transduction of innate immune signals. Both genes are single copy and ARD1, the putative catalytic component, is expressed in both bloodstream-form and insect-stage cells. Dynamic changes of the endogenous cannabinoid and opioid mesocorticolimbic systems during adolescence: THC effects. Cardiovascular monitoring: clinical applications of technologic advancements.

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Further evidence for mitochondrial dysfunction in progressive supranuclear palsy. Proximity-dependent biotin identification (BioID) is a recently developed technique that allows forward screens for interaction partners and near neighbors in a native environment with no requirement for solubility in nonionic detergent. women) had greater activation in brain areas associated with motor control regions (e.g. Peripheral blood mononuclear cells (PBMCs) from 36 RA patients and 30 control participants were analysed by flow cytometry for EPCs defined by the expression of CD34/CD133, CD34/CD117, CD34/CD31, CD34/KDR and CD34/CD133/KDR.

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In a prospective study of 43,117 people, prescriptions issued by general practitioners over two years were linked with records of hospital admissions and deaths. Our results show that low ASA activity is more frequently found in psychiatric patients than in control subjects. To address the limitations of traditional pathogen detection methodologies in clinical diagnosis, scientists have developed oligonucleotide microarrays. Fungi intrusions into sub-stomal cavities of the oat and wheat leaves are predominantly prevented by oxidative burst and to the less extent by defense proteins. Significant effects on bone metabolism are produced due to cancer treatment especially of breast and prostate origin, even in the absence of bone metastases.

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We analyzed 23 patients (10 diabetic and 13 nondiabetic) with coronary artery disease and without known cardiac autonomic neuropathy. To report the clinical case of a 65-year-old male who developed retinal dysfunction following cobalt-chromium toxicity. However, mechanisms of action and surrogate immunologic markers of efficacy have not been reported thus far.

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Side effects of HpD, such as skin rash, were noted in two patients, but no serious complications of PDT were encountered. This type of screening can save a significant number of NSCLC patients from inappropriate or unnecessary thoracotomy and further staging procedures with their associated morbidity and risk. Two novel TSC2 mutations in Chinese patients with tuberous sclerosis complex. Pyogenic granuloma of unusual size with alveolar resorption in a 75-year-old patient.

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The use of elimination diets to identify these dietary antigens can be instrumental in both diagnosis and effective treatment for these disorders. Eighteen adults with hemiparesis secondary to supraspinal lesions served as subjects for the standing portion of the study.

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Direct evidence for pH-dependent Fc receptors on proximal enterocytes of suckling rat gut. At higher concentrations of the reactants than those present in the ICSH-recommended reagents, this reaction proceeds also at room temperature. More research is needed on the natural history of depression seen in the community, as well as on treatment and outcome. Weanling W/Fu rats were inoculated intraperitoneally with 1 X 10(6) to 1 X 10(7) (C58NT)D Gross virus-induced lymphoma cells. Several recent studies have associated iPLA2 inactivation with neurodegenerative diseases, suggesting the possibility that products of the iPLA2 reaction as potential treatments for these disorders.

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The only exception is the process, in which biosynthesis is directly connected with the culture growth rate. The theory and experiment presented in the present paper may help in the development of solid-state NMR methods for studying interhelical contacts in membrane proteins, as well as for their spectral assignment. Protection of cisplatin-induced spermatotoxicity, DNA damage and chromatin abnormality by selenium nano-particles. Results of this study are in good agreement with the standard air conduction threshold sound pressure levels (ANSI) and with bone conduction threshold force levels reported in the literature. Displacement of the bromine atom with nucleophiles, under suitable reaction conditions, occurs without epimerization of starting compounds, giving (R,R)-2-substituted carboxylic acid derivatives.

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Outbreaks of hepatitis A and emergence of new AIDS-associated agents: the need to add terminal 100 degrees C dry-heat sterilization to factor VIII and factor IX concentrates. Three of the 13 TSP/HAM sera and 1 of the 17 asymptomatic sera contained HTLV-I-specific IgM antibodies, whereas 6 and 5 sera, respectively, contained IgA antibodies. The results from this study suggest that nutrient enrichment and adequate temperatures are important factors shaping Cx. The purpose was to assess whether changes in cerebropetal blood flow caused by an ICA occlusion have an effect on clinical symptoms and cerebral metabolism. The joint goals of quality improvement and cost control can best be realized if institutions and practitioners embrace these new approaches and use them to enhance their performances.

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Association of catheterization with acute kidney injury in the cardiac surgical patient. Determination of pulmonary arterial pressure and pulmonary vasoconstrictive responses to hypoxia in healthy Tibetan men Laboratory studies with BL-S 578 (Cefadroxil) a new broad-spectrum orally active cephalosporin.

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The neuropsychological investigation suggests that carbon monoxide amnesia shares common features with hippocampal amnesia, namely a discrepancy between a normal Short-Term Memory (STM) and a hampered Long-Term Memory (LTM). The influence of chromatin compactness on the stoichiometry of the Feulgen-Schiff procedure studied in model films. Mice were immunized by gene-gun immunization with recombinant plasmid and cefpodoxime costco two other adjuvant plasmids that express granulocyte/macrophage colony-stimulating factor and FMS-like tyrosine kinase 3 ligand, respectively.

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Carbon agglomeration reaction as a method of identification of meningococci The hearing performance inventory and hearing aid use in allopurinol norman 300 mg profound hearing loss.

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Introduction to artificial neural networks for physicians: taking the lid off the black box. The clearance from the liver of a bolus of 133Xe was monitored using a gamma-ray camera so that blood flow from different areas of the liver could be calculated. Cases that are refractory or resistant to BCG therapy are a management dilemma with various carisoprodol side effects withdrawal from birth available treatment options. In developing countries, like Nigeria, non-communicable diseases including endocrine disorders are on the increase.